本文报道采用离子交换柱层析分离法,作肌酸比色法定量测定27例临床诊断急性早期心肌炎和23例疑似心肌炎患儿血清肌酸激酶(CK)-MB同功酶活性,结果与33例对照组比较,差异非常显著(P<0.001)。发病第1周CK-MB即可升高,第2周阳性率及峰值最高,多在1月内转阴。CK-MB的敏感性和特异性高于CK总活性,适于心肌炎的早期诊断。 This article reports the determination of serum creatine kinase (CK) -MB isoenzyme activity in 27 cases of acute early myocarditis and 23 cases of suspected myocarditis by ion exchange column chromatography for the quantitative determination of creatine colorimetry in 27 cases. The results were consistent with 33 Cases of control group, the difference was significant (P <0.001). The first week of onset of CK-MB can be increased, the first two weeks the highest positive rate and peak, mostly negative in January. CK-MB sensitivity and specificity higher than the total activity of CK, suitable for early diagnosis of myocarditis.