随着应用生物活性物质治疗癌症及其他疾病的增多,这类物质的神经毒性也渐引起了人们的重视。在应用α-干扰素(IFN-α)治疗癌症、肝炎、肌萎缩侧索硬化症等方面,有关神经毒性的报道很多。本文报道14例因癌症而应用IFN-α治疗出现神经毒性的临床研究资料。本组病人年龄28～61岁。IFN-α的用量从3×10~6U 每周注射3次到10×10~6U 每天注射 With the application of biologically active substances in the treatment of cancer and other diseases, the neurotoxicity of these substances has gradually attracted people’s attention. In the application of interferon alpha (IFN-α) for the treatment of cancer, hepatitis, amyotrophic lateral sclerosis and other aspects of neurotoxicity has been reported. This article reports 14 cases of cancer due to the application of IFN-α treatment of neurotoxicity clinical research data. The patients aged 28 to 61 years old. The dosage of IFN-α was injected from 3 × 10 ~ 6U three times a week to 10 × 10 ~ 6U daily