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目的阐述系统性红斑狼疮中枢神经系统受累的临床特点,避免误诊误治。方法通过病例分析探讨系统性红斑狼疮中枢神经系统受累的临床特点、发病机制及治疗方法。结果所选病例除中枢神经系统表现外,还合并其他多系统损害,多种自身抗体阳性,抗生素治疗无效,对激素反应好。结论中枢神经系统症状可为系统性红斑狼疮的首发表现,应注意完善相关检查进行诊断与鉴别诊断,及时给予大剂量糖皮质激素治疗。
Objective To describe the clinical features of central nervous system involvement in systemic lupus erythematosus and avoid misdiagnosis and mistreatment. Methods To investigate the clinical features, pathogenesis and treatment of central nervous system involvement in systemic lupus erythematosus through case analysis. Results In addition to the central nervous system performance, selected cases also combined with other multi-system damage, a variety of autoantibodies positive, antibiotic treatment ineffective, good response to hormones. Conclusion The central nervous system symptoms may be the first manifestation of systemic lupus erythematosus, should pay attention to improve the relevant examination for diagnosis and differential diagnosis, timely administration of high-dose glucocorticoid therapy.