论文部分内容阅读
目的对2006年广州市流行性感冒(流感)监测结果进行分析。方法病例标本来自广州市4家哨点医院的流感样病例和暴发疫点现患病例的漱口液或咽拭子,采用犬肾传代细胞进行病毒分离;人群血清标本于3月和10月在其中一家哨点医院按年龄组分层随机抽取健康体检人群进行采集,采用微量半加敏红细胞抑制试验检测各型流感抗体。结果1143份哨点医院采集的标本中有95份(8.31%)分离出流感病毒(H1N1型80株,B型15株);接到暴发疫情146起,罹患率0.40%~16.97%。疫情主要发生在3-4月,全市12个区(市)均有报告且全部来自学校。人群血清抗体H3N2、B(维多利亚系)、B(巴拿马系)型阳性率两次监测结果无统计学差异,但H1N1抗体10月高于3月(χ2=41.94,P<0.05)。结论广州市2006年流感流行优势毒株为H1N1;暴发疫情的流行高峰出现在3-4月,以局部暴发为主要特征;学校等集体单位应加强流感监测;B型流感病毒在广州地区仍有继续引起局部暴发流行的潜在危险。
Objective To analyze the surveillance results of influenza (influenza) in Guangzhou in 2006. Methods Case samples were collected from 4 sentinel hospitals in Guangzhou and 2 outpatients with outbreaks or outbreaks of mouthwash or throat swabs. Canine kidney passage cells were used for virus isolation. Serum samples from March to October In one of the sentinel hospitals, the health check-up population was randomly selected according to the age group to collect the samples, and the various semi-sensitized erythrocyte inhibitory tests were used to detect various types of influenza antibodies. Results Of the 1143 sentinel hospitals, 95 (8.31%) of the specimens collected from the sentinel hospitals isolated influenza virus (80 strains of H1N1 and 15 of type B). The number of outbreaks was 146 and the attack rate was 0.40% ~ 16.97%. The outbreak mainly occurred from March to April, with reports from all 12 districts (cities) in the city and all from schools. There was no significant difference in the positive rates of serum H3N2, B (Victoria) and B (Panama) in the population, but the H1N1 antibody was higher in October than in March (χ2 = 41.94, P <0.05). Conclusions The epidemic predominant strain of H1N1 in Guangzhou was H1N1 in 2006; the peak of the outbreak was in March-April, with the outbreak as the main characteristic; the collective units such as schools should strengthen the surveillance of influenza; the type B influenza virus still remained in Guangzhou Continue to pose a potential risk of a local outbreak.