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目的:对埃索美拉唑、枸橼酸莫沙必利联合治疗老年胃食管反流病的治疗效果进行观察与分析。方法:将我院在2014年3月至2016年3月期间接受治疗的60例老年胃食管患者选取为本次的研究对象,将所有患者按照随机数字表法分为对照组与研究组,每组各30例。对照组患者采用埃索美拉唑进行治疗,研究组患者采用埃索美拉唑、枸橼酸莫沙必利联合治疗,疗程为4周,对两组患者在治疗后的效果与不良反应发生率进行比对分析。结果:两组患者的不良反应发生率相比较没有显著差异,P>0.05,差异不具有统计学意义;研究组患者治疗的总有效率明显的高于对照组,两组间相比有显著差异,P<0.05,差异具有统计学意义。结论:对老年胃食管反流病患者采用埃索美拉唑、枸橼酸莫沙必利联合治疗有显著的治疗效果,并且具有很高的安全性,提高了患者的生活质量,在临床上值得推广应用。
Objective: To observe and analyze the therapeutic effect of esomeprazole and mosapride citrate in the treatment of senile gastroesophageal reflux disease. Methods: 60 elderly patients with gastroesophageal reflux disease treated in our hospital from March 2014 to March 2016 were selected as the study subjects, all patients were divided into control group and study group according to random number table method Group of 30 cases. The patients in the control group were treated with esomeprazole. The patients in the study group were treated with esomeprazole and mosapride citrate for 4 weeks. The effects and adverse reactions of the two groups of patients after treatment Rate comparison analysis. Results: There was no significant difference in the incidence of adverse reactions between the two groups, P> 0.05, the difference was not statistically significant; the total effective rate of treatment group was significantly higher than that of the control group, there was significant difference between the two groups , P <0.05, the difference was statistically significant. Conclusion: The combination therapy of esomeprazole and mosapride citrate in elderly patients with gastroesophageal reflux disease has a significant therapeutic effect, and has high safety and improves the quality of life of patients, in clinical practice Worth promoting application.