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利用醛(酮)肟与2-氯-4-取代-5-噻唑甲酰氯反应,合成了8个含2-氯-4-取代噻唑环核的肟酯类化合物,所有化合物的结构均经1H NMR,13C NMR及元素分析确证。离体杀菌活性测试结果表明,目标化合物有一定的杀菌活性。
Eight oxo-ester compounds containing 2-chloro-4-substituted thiazole nuclei were synthesized by the reaction of aldehyde (keto) oxime with 2-chloro-4-substituted-5-thiazolecarbonyl chloride. All compounds were characterized by 1H NMR, 13C NMR and elemental analysis confirmed. In vitro bactericidal activity test results show that the target compound has a certain bactericidal activity.