论文部分内容阅读
以免疫组化法研究Fas配体（L）在丙型肝炎病人肝组织内的表达情况，发现在碎屑样坏死（PN）、桥样坏死（BN）及灶性坏死区浸润的单个核细胞有明显的FasL表达，阳性率为41．2％。FasL阳性细胞与肝脏炎症分级程度密切相关，G0－1；组与G3－4组比较有显著差异。FasL在肝细胞内亦有表达，表达程度似与炎症程度有关。不论是Fas或FasL在慢性丙肝中的表达均较急性肝炎显著，提示在病程慢性化中可能起着重要作用。
Immunohistochemistry was used to study the expression of Fas ligand (L) in the hepatic tissue of patients with hepatitis C, and it was found that in mononuclear cells infiltrating with debris-like necrosis (PN), bridging necrosis (BN) and focal necrosis Obvious FasL expression, the positive rate was 41.2%. FasL positive cells and liver inflammation are closely related to the degree of grading, G0-1; group and G3-4 group were significantly different. FasL also expressed in hepatocytes, the degree of expression may be related to the degree of inflammation. Both Fas or FasL expression in chronic hepatitis C than acute hepatitis significantly, suggesting that chronic disease may play an important role.