外伤性视神经损伤发病率约为0.3%~5.2%,临床上主要治疗方法糖皮质激素和视神经管减压术等均不能有效阻止视神经萎缩的发生~([1])。多数患者预后不良,大约50%患者最终失明~([2]),因此临床迫切需要明确视神经伤后细胞修复过程、影响因素,运用安全有效的治疗手段。本研究以白兔的动物模型为研究对象,观察计数视网膜神经节细胞Caspase-3受体阳性表达,来评价临床治疗有效 The incidence of traumatic optic nerve injury is about 0.3% ~ 5.2%, the main clinical treatment of glucocorticoid and optic canal decompression, etc. can not effectively prevent the occurrence of optic atrophy ~ ([1]). Most patients with poor prognosis, about 50% of patients eventually blind ~ ([2]), so the urgent need to clinically clear cell repair after optic nerve injury, affecting factors, the use of safe and effective treatment. In this study, we studied the expression of Caspase-3 receptor in retinal ganglion cells in rabbits to evaluate the clinical efficacy