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众所周知 ,任何化疗药物在杀伤肿瘤细胞的同时 ,都会大量杀死增殖活跃的消化道粘膜上皮细胞 ,轻者引起患者食欲下降 ,重者则引起剧烈恶心呕吐。低剂量胃复安 (10～2 0ｍｇ)对化疗恶心呕吐无明显疗效 ,新型高选择性强力止吐药枢复宁预防化疗恶心呕吐的有效率也仅在 5 0 %左右。
It is well-known that any chemotherapeutic agent kills and kills the tumor cells, and it will kill a large number of actively proliferating gastrointestinal mucosal epithelial cells. The light causes the loss of appetite, while the severe cases cause severe nausea and vomiting. Low-dose metoclopramide (10 ~ 20mg) has no obvious curative effect on nausea and vomiting after chemotherapy. The efficacy of the new type of high-selective and powerful antiemetic pharmacokinetics for prevention of chemotherapy nausea and vomiting is only about 50%.