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为了探讨多发性骨髓瘤伴发淀粉样变性的罕见病例的有效治疗方法。对1例58岁的伴发四肢淀粉样变性的多发性骨髓瘤老年患者进行了包括血液免疫检查在内的多项实验室检查,骨髓穿刺和活检,以及全骨髓显象等检查,在治疗方面给予化疗药物治疗和自体造血干细胞移植。结果显示:自体造血干细胞移植后23天患者骨髓造血恢复,免疫固定电泳正常,骨髓穿刺浆细胞占0.6%。结论:自体造血干细胞移植是治疗伴发四肢淀粉样变性的多发性骨髓瘤的有效方法。
In order to explore the effective treatment of rare cases of multiple myeloma with amyloidosis. A case of 58-year-old elderly patients with multiple myeloma with amyloidosis underwent multiple laboratory tests including blood tests for immunity, bone marrow aspirate and biopsy, and whole bone marrow imaging. In terms of treatment Give chemotherapy drugs and autologous hematopoietic stem cell transplantation. The results showed that the bone marrow hematopoiesis restored after 23 days of autologous hematopoietic stem cell transplantation and the immune fixed electrophoresis was normal. The bone marrow puncture plasma cells accounted for 0.6%. Conclusion: Autologous hematopoietic stem cell transplantation is an effective method for the treatment of multiple myeloma with amyloidosis in the extremities.