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目的:观察麻杏石甘汤联合常规疗法治疗中枢性高热的疗效。方法:选取60例中枢性高热肺热壅盛证患者,随机分为治疗组和对照组各30例,2组均予吸氧、冰帽、酒精擦浴等物理降温治疗,并给予脱水、营养保护脑细胞等常规药物治疗,有手术指征者行手术治疗,治疗组在此基础上加用麻杏石甘汤,2组疗程均为10天,监测记录2组患者的日最高体温、日体温平均值,并记录退热起效时间、完全退热时间、体温反弹例数。结果:治疗组总有效率为100%,高于对照组的73.33%,差异有统计学意义(P<0.01)。治疗第1天开始至第10天,2组日最高体温及日平均体温均逐渐下降,与治疗前比较,差异均有统计学意义(P<0.05),治疗组日最高体温及日平均体温均低于同期对照组(P<0.05)。治疗组退热起效时间及完全退热时间均较对照组缩短,差异均有统计学意义(P<0.05)。治疗组患者均未出现体温反弹,而对照组有8例患者出现了体温反弹,2组体温反弹率比较,差异有统计学意义(P<0.01)。结论:在常规疗法基础上加用麻杏石甘汤治疗中枢性高热效果显著,退热快,综合疗效优于单纯使用西药治疗。
Objective: To observe the effect of Maxing Shigan Decoction combined with conventional therapy on central hyperthermia. Methods: Sixty patients with central hyperthermia and hyperthermia were randomly divided into treatment group (30 cases) and control group (30 cases). Both groups were given physical therapy such as oxygenation, ice cap and alcohol rubbing bath, and given dehydration and nutrition Protection of brain cells and other conventional drug treatment, surgical indications were surgical treatment, the treatment group on this basis with the addition of Maxing Shigan Tang, two groups were 10 days treatment, monitoring recorded two groups of patients with the highest body temperature, day Average body temperature, and record the onset of fever, complete antipyretic time, body temperature rebound number. Results: The total effective rate of the treatment group was 100%, which was higher than that of the control group (73.33%), the difference was statistically significant (P <0.01). From the first day to the tenth day of treatment, the highest body temperature and daily average body temperature decreased gradually in both groups, which were significantly different from those before treatment (P <0.05). The highest body temperature and average body temperature Lower than the control group (P <0.05). The onset time of antipyretic and the complete antipyretic time in the treatment group were shorter than those in the control group, with significant differences (P <0.05). There was no body temperature rebound in the treatment group, while 8 patients in the control group appeared body temperature rebound. The body temperature rebound rate in the two groups was statistically significant (P <0.01). Conclusion: The addition of Maxingshigan Decoction on the basis of conventional therapy has significant effect of central hyperthermia, rapid fever, and the comprehensive curative effect is better than that of western medicine alone.