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目的探讨医护一体化护理模式对预防骨科大手术术后深静脉血栓形成的意义，总结该模式的临床价值。方法将132例骨科大手术患者随机分为对照组和观察组各66例，对照组给予常规护理，观察组给予医护一体化护理模式干预，比较两组患者术后深静脉血栓发生率及患者住院满意度差异。结果观察组下肢深静脉血栓形成率4.55%，显著低于对照组12.1%。用SPSS16.0软件统计两组患者满意度得分总分，观察组满意度得分（均数±标准差）=66.82±6.96，对照组得分（均数±标准差）=58.36±15.28，=0.005，两组存在统计学差异。结论开展医护一体化护理模式，能有效预防骨科大手术后下肢深静脉血栓形成，提高患者满意度，深化工作内涵，值得推广。“,”Objective To evaluate the clinical effect of medical integration in prevent orthopaedic postoperative deep vein thrombosis. Methods Randomly divide 132 patient who will accept the big orthopedic operation into two groups. The experimental group (n=66), who were given medical integration in the whole treatment process. Then the control group(n=66) were given conventional nursing model. The rate of deep vein thrombosis and the satisfaction of two groups were compared. Results Experimental group of deep vein thrombosis rate was 4.55%, significantly lower than the control group was 12.1%. SPSS16.0 software was applied to statistic two groups of patient satisfaction score, the experimental group satisfaction score (mean±standard deviation)=66.82±6.96, and the control group=58.36±15.28,=0.005,statistical differences in the two groups. Conclusion Medical integration model can effectively prevent orthopaedic deep venous thrombosis after the big orthopedic operation, improve patient satisfaction, is worth promoting.