19世纪末已发现生长发育与垂体腺有关,并在实验动物中得到证实,但垂体中促进生长的物质是什么还不清楚。1943年Evans 建立了生长激素(GH)的胫骨生物学测定法。李卓浩等分别在1944和1956年提纯了牛和人 GH(HGH)。1962年 Hunter 等建立了 HGH 的放射免疫测定方法。此后科学家们对 HGH 的化学结构、理化性质、生理作用、生理和病理情况下的分泌及调节进行了广泛的研究,并应用于临床 HGH 功能紊乱疾病的诊断和治疗。 The late 19th century has been found that the growth and development of the pituitary gland, and confirmed in experimental animals, but to promote growth in the pituitary is what is unclear. Evans established the tibial bioassay for growth hormone (GH) in 1943. Li Zhuohao and others purified cow and human GH (HGH) in 1944 and 1956, respectively. In 1962, Hunter et al. Established a radioimmunoassay for HGH. Since then, scientists have extensively studied the chemical structure, physicochemical properties, physiological functions, secretion and regulation of HGH in HGH and applied it to the diagnosis and treatment of clinical HGH dysfunction diseases.