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目的探讨经鼻间歇正压通气在早产儿呼吸窘迫综合征初始治疗中的应用效果。方法选取2012—2013年大同市第一人民医院收治的行机械通气初始治疗的呼吸窘迫综合征患儿80例,随机将患者分为观察组与对照组,每组40例。观察组患儿给予经鼻间歇正压通气治疗,对照组患儿给予经鼻持续气道正压通气治疗,比较两组患儿治疗效果、治疗前后pH值及氧合指数(OI)、平均上机时间。结果观察组患儿治疗效果优于对照组(P<0.05)。治疗前两组患儿pH值、OI比较,差异无统计学意义(P>0.05);治疗后观察组患儿pH值、OI高于对照组(P<0.05)。观察组患儿上机时间短于对照组(P<0.05)。结论经鼻间歇正压通气在早产儿呼吸窘迫综合征初始治疗中的应用效果确切,有利于患儿呼吸功能恢复,缩短上机时间。
Objective To investigate the effect of nasal intermittent positive pressure ventilation in the initial treatment of respiratory distress syndrome in premature infants. Methods Eighty children with respiratory distress syndrome who underwent initial mechanical ventilation were enrolled in the First People’s Hospital of Datong City from 2012 to 2013. The patients were randomly divided into observation group and control group with 40 cases in each group. The patients in the observation group were given nasal intermittent positive pressure ventilation and the control group were given nasal continuous positive airway pressure ventilation. The therapeutic effect, the pH and oxygenation index (OI) before and after treatment were compared between the two groups. On average, Machine time. Results The therapeutic effect of observation group was better than that of control group (P <0.05). There was no significant difference in pH and OI between the two groups before treatment (P> 0.05). After treatment, the pH value and OI in observation group were higher than those in control group (P <0.05). The observation group was shorter than the control group (P <0.05). Conclusion nasal intermittent positive pressure ventilation in premature infants with respiratory distress syndrome initial treatment effect is exact, is conducive to children with respiratory function recovery, shorten the machine time.