扑米酮及其片剂在浓硫酸、硫酸钾及无水硫酸铜的存在下,消解转化成铵盐,于浓碱下逸出NH_3,可用氨气敏电极测定;在1×10~(-2)～1×10~(-5)M浓度范围内校正曲线呈线性,平均百分回收率为100.2±0.65,变异系数为O.50%;三批商品片测定值均获得与中国药典(1985年版)法接近的结果。本法简便准确,适于某些含氮药物的常规分析。 In the presence of concentrated sulfuric acid, potassium sulfate and anhydrous copper sulfate, primidone and its tablets are digested and converted into ammonium salts, and NH3 is released under concentrated alkali, which can be measured by ammonia gas sensing electrode. When the concentration is 1 x 10 ~ (- 2) to 1 × 10 ~ (-5) M, the average recovery was 100.2 ± 0.65 and the coefficient of variation was O.50% 1985 version) Law close to the result. This method is simple and accurate, suitable for routine analysis of certain nitrogen-containing drugs.