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目的:探讨应用单腔起搏器治疗血管迷走性晕厥(VVS)的效果。方法:将确诊为VVS的患者42例,随机分为起搏器组(22例)和药物治疗组(20例)进行疗效对照。起搏器组置入单腔起搏器(VVI 10例,VVIR12例),药物治疗组口服美托洛尔治疗。2组患者出院后6个月均复查直立倾斜试验并随访,观察对晕厥的预防效果。结果:起搏器组直立倾斜试验阴转率82.0%,无一例发生晕厥,2例仍有晕厥先兆,但症状明显减轻;药物治疗组直立倾斜试验阴转率50.0%,8例发生晕厥,但发作次数减少。2组直立倾斜试验阴转率和晕厥发生率比较,差异均有统计学意义(P<0.01)。结论:对于反复发作的VVS患者,安装起搏器可以有效防止晕厥的发生,药物治疗亦有一定疗效,但不能完全防止晕厥的发生。
Objective: To investigate the effect of single chamber pacemaker treatment of vasovagal syncope (VVS). Methods: Forty-two patients diagnosed with VVS were randomly divided into a pacemaker group (n = 22) and a drug treatment group (n = 20). Pacemaker group into a single-chamber pacemaker (VVI 10 cases, VVIR12 cases), the drug treatment group oral metoprolol treatment. Two groups of patients were reviewed 6 months after erection upright tilt test and follow-up to observe the prevention of syncope. Results: The negative conversion rate was 82.0% in the vertical tilt test of the pacemaker group. No syncope occurred and 2 cases still had the signs of syncope. However, the symptoms were relieved. The negative conversion rate was 50.0% in the vertical tilt test group and 8 cases occurred syncope in the medication group The number of seizures decreased. There was significant difference in negative conversion rate and syncope incidence between the two groups (P <0.01). Conclusion: For patients with recurrent VVS, the installation of pacemaker can effectively prevent the occurrence of syncope, drug treatment also has some effect, but can not completely prevent the occurrence of syncope.