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目的 :测定急性脑血栓形成患者血清白细胞介素 - 10 (IL - 10 )的水平 ,探讨其临床意义。方法 :采用ELISA检测 5 0例病情不同程度脑血栓形成患者血清IL - 10的水平及变化 ,以 30例正常人 (对照组 )作比较。结果 :发病初期脑血栓组血清IL - 10水平显著低于对照组 (P <0 0 1) ,且随脑梗死程度加重而加重 (P <0 0 1) ,(7～ 10 )天后IL - 10水平上升。结论 :脑血栓形成可能与患者血清IL - 10水平低有关。
Objective: To determine the level of serum interleukin - 10 (IL - 10) in patients with acute cerebral thrombosis and to investigate its clinical significance. Methods: Serum levels of IL - 10 and its changes in 50 patients with different degrees of cerebral thrombosis were detected by ELISA, and 30 healthy controls (control group) were compared. Results: The level of IL - 10 in the early stage of cerebral infarction was significantly lower than that in the control group (P <0.01), and increased with the degree of cerebral infarction (P <0.01) Rise. Conclusion: Cerebral thrombosis may be related to the low level of serum IL - 10 in patients.