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癌组织浸润横纹肌,多在肌纤维间结缔组织内浸润,直接侵入肌纤维内并继续繁殖生长——肌纤维内转移,是极为罕见的现象,本文报道一例乳腺癌转移至横纹肌纤维内。 病理报告 女姓,61岁,五年前因患左侧乳腺癌已作根治术。近两月来觉左胸壁有白豆大肿物,手术见肿物位于胸大肌浅层,质硬,灰白色。 病理检查:例号C75279,肉眼为灰白色绿豆大质硬组织,镜下为肌肉及脂肪组织。在脂肪及肌肉内的结缔组织内均有癌细胞浸润。癌细胞中等大小,圆形或多角形,核深染而胞浆少,符合乳腺单纯癌。比较特别者是见到癌细胞侵入肌纤维内。受累肌纤维异常肿大,癌细胞数目多少不一,多者可以充满整段肌纤维,且占据肌细胞的大部分,周围肌浆可液化而成囊泡状或剩下少许肌浆在外围包绕癌细胞(图1、图2)。
Infiltration of striated muscle in cancer tissue, and more in the intermuscular connective tissue infiltration, direct infiltration of muscle fibers and continue to grow and grow - intramuscular transfer, is an extremely rare phenomenon, this article reported a case of breast cancer metastasis to striated muscle fibers. Pathology report The female surname, 61 years old, has undergone radical surgery for suffering from left breast cancer five years ago. In the past two months, there has been a large white-bean mass on the left chest wall. The operation showed that the mass was located in the pectoralis major muscle and it was hard and gray. Pathological examination: Case No. C75279, with macroscopic hard tissues of gray mung bean, and muscle and adipose tissue. Infiltration of cancer cells occurs in both fat and intramuscular connective tissue. The cancer cells are of medium size, round or polygonal, with deep staining of the nucleus and less cytoplasm, consistent with simple breast cancer. It is more special to see cancer cells invade the muscle fibers. The affected muscle fibers are abnormally swollen. The number of cancer cells is not the same. Many of them can fill the entire muscle fibers and occupy most of the muscle cells. The surrounding sarcoplasm can be liquefied to form vesicles or a little sarcoplasmic muscle around the tumor. Cells (Figure 1, Figure 2).