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目的通过对中医外科外用散剂组方中药抗菌作用的细菌学研究,研究其体外抗菌谱及抗菌力。方法检索传统方、各医院的协议方,对52首方剂中出现的60味中药,进行体外抗菌作用细菌学研究。结果实验药物之间无明显拮抗现象。绝大多数中药抗菌谱窄、抗菌力低;汞、铅等化合物形成的丹类药物抗菌谱广、抗菌力强。结论活血化瘀类药物抗菌谱广,抗菌作用弱;矿物质类药材中的龙骨、滑石、石膏无抗菌作用。清热解毒药物类抗菌谱窄,抗菌作用差。
OBJECTIVE To study the antimicrobial spectrum and antibacterial activity in vitro by the bacteriological study on the antimicrobial effect of traditional Chinese medicine powder for external use. Methods The traditional prescriptions and protocol of each hospital were searched and the antimicrobial bacteriological studies in vitro were carried out on 60 Chinese herbs appearing in 52 prescriptions. Results There was no obvious antagonism between experimental drugs. The vast majority of traditional Chinese medicine antibacterial spectrum narrow, low antibacterial; mercury, lead and other compounds formed Dan antibacterial wide spectrum of drugs, strong antibacterial. Conclusion The blood-activating and stasis-removing drugs have wide antibacterial spectrum and weak antibacterial effect. The keel, talc and gypsum in mineral medicine have no antibacterial effect. Qingrejiedu antimicrobial spectrum antibacterial narrow, poor antibacterial effect.