参苓益气散联合西药治疗脾胃虚弱型慢性腹泻随机平行对照研究

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[目的]观察参苓益气散联合西药治疗脾胃虚弱型慢性腹泻疗效。[方法]使用随机平行对照方法,将80例门诊患者按病志号抽签法简单随机分为两组。对照组40例常规对症支持治疗,纠正水盐及电解质平衡紊乱,抗感染及胃肠黏膜保护。治疗组40例参苓益气散(党参、茯苓各50g,淮山药30g,砂仁、白术各20g,桔梗10g,甘草6g,腹胀重加麦芽10g;恶寒重加干姜10g),1剂/d,水煎150m L,3次/d;西药治疗同对照组。两组均连续治疗42d为1疗程。观测临床症状、中医症状积分、便常规、不良反应。连续治疗2疗程,判定疗效。[结果]治疗组痊愈22例,有效17例,无效1例,总有效率97.50%。对照组痊愈10例,有效17例,无效13例,总有效率67.50%。治疗组疗效优于对照组(P<0.01)。[结论]参苓益气散联合西药治疗脾胃虚弱型慢性腹泻,疗效满意,无副作用,值得推广。 [Objective] To observe the curative effect of Shenling Yiqi Powder combined with Western medicine on chronic diarrhea of ​​spleen and stomach. [Methods] Using randomized parallel control method, 80 outpatients were randomly divided into two groups according to the random number drawing method. Control group of 40 patients with conventional symptomatic supportive treatment, to correct water and salt and electrolyte balance disorders, anti-infection and gastrointestinal mucosal protection. The treatment group 40 cases of Shenling Yiqi San (Codonopsis, Poria each 50g, 30g yam yam, Amomum, Atractylodes each 20g, Campanulaceae 10g, licorice 6g, abdominal distension plus malt 10g; aversion to add ginger 10g), 1 / d, decoction 150m L, 3 times / d; Western medicine treatment with the control group. Both groups were treated for 42 days for a course of treatment. Observation of clinical symptoms, symptoms of traditional Chinese medicine, it is routine, adverse reactions. Continuous treatment of 2 courses to determine the efficacy. [Results] In the treatment group, 22 cases were cured, 17 cases were effective, 1 case was ineffective and the total effective rate was 97.50%. The control group recovered 10 cases, effective in 17 cases, ineffective in 13 cases, the total effective rate was 67.50%. The treatment group than the control group (P <0.01). [Conclusion] Shenling Yiqi Powder combined with western medicine is effective in treating chronic diarrhea due to spleen and stomach deficiency. It is worthy of promotion.
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