论文部分内容阅读
目的观察加味血腑逐瘀颗粒剂治疗急性心肌梗死(AMI)的临床疗效及对炎症反应标志物超敏C-反应蛋白(hs-CRP)的影响。方法将64例患者随机分为两组:对照组32例,给于常规治疗;治疗组32例,在常规治疗基础上加用加味血腑逐瘀颗粒剂6g。观察两组患者治疗后的病死率、心脏缺血相关事件发生率及血清超敏C-反应蛋白的变化。结果治疗组缺血相关事件发生率明显下降(P<0.05);超敏C-反应蛋白较治疗前显著下降,与对照组相比有统计学意义(P<0.05)。结论加味血腑逐瘀颗粒剂治疗急性心肌梗死安全有效,其机制可能与其降低患者血清hs-CRP水平,抑制AMI的血管炎性反应,稳定斑块有关。
Objective To observe the clinical efficacy of Modified Fufang Zhuyu Granule in the treatment of acute myocardial infarction (AMI) and its effect on the expression of high sensitivity C-reactive protein (hs-CRP). Methods Sixty-four patients were randomly divided into two groups: control group, 32 cases, for routine treatment; treatment group, 32 cases, on the basis of conventional treatment plus Jiaweizhufu Zhuyu granules 6g. The mortality, the incidence of cardiac ischemia-related events and the changes of serum high-sensitivity C-reactive protein in the two groups were observed. Results The incidence of ischemia-related events in the treatment group decreased significantly (P <0.05). Hypersensitive C-reactive protein was significantly decreased compared with that before treatment (P <0.05). Conclusion Modified Fufang Zhuyu granules for the treatment of acute myocardial infarction safe and effective mechanism may be related to its lower serum hs-CRP levels, inhibition of AMI vascular inflammation, stable plaque related.