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目的研究鼻内镜鼻窦手术后醋酸曲安奈德注射迎香穴的疗效和安全性。方法在住院准备行手术的慢性鼻窦炎鼻息肉病人中随机设置对照组A、B和研究组各50例,对照组A术后予常规处理,对照组B术后强的松30mg口服14d,研究组术后第1天用醋酸曲安奈德注射双侧迎香穴1次(每侧各20mg),在术后第3、6、12个月进行症状和鼻内镜评分,监测血糖和胃肠道症状等副作用。结果术后第3个月研究组和对照组B的症状和鼻内镜评分都显著优于对照组A(P<0.05),但这两组间差异无统计学意义(P>0.05),第6、12个月症状和鼻内镜评分三组差异无统计学意义(P>0.05)。术后第15天,对照组B血糖高于另外两组(P<0.05),术后第30天,三组间差异无统计学意义(P>0.05)。3例对照组B患者和1例研究组患者出现胃肠不适,在抗酸治疗后症状消失。未观察到有其他并发症的发生。结论鼻内镜鼻窦手术后醋酸曲安奈德注射迎香穴可促进症状和术腔恢复,安全性好。
Objective To study the efficacy and safety of triamcinolone acetonide injection at Ying-Ying Point after endoscopic sinus surgery. Methods 50 cases of chronic sinusitis and nasal polyps who were hospitalized for surgery were randomly divided into control group A and group B and study group 50 cases. Control group A received conventional treatment after treatment and group B was given prednisone 30 mg orally for 14 days. On the first postoperative day, the patients were injected with triamcinolone acetonide once a day (20mg on each side), symptoms and endoscopies were scored on the 3rd, 6th and 12th month after operation, blood glucose and gastrointestinal Symptoms and other side effects. Results The symptoms and endoscopic score of study group B and control group B were significantly better than that of control group A at the third month after operation (P <0.05), but there was no significant difference between the two groups (P> 0.05) There was no significant difference in symptom and endoscopic score between 6 and 12 months (P> 0.05). On the 15th day after operation, the blood glucose in control group B was higher than the other two groups (P <0.05). On the 30th day after operation, there was no significant difference among the three groups (P> 0.05). Gastrointestinal discomfort was noted in 3 patients in control group B and in 1 patient in the study group, and disappeared after antacid treatment. No other complications were observed. Conclusion The injection of triamcinolone acetonide to Yingxiang acupoint after nasal endoscopic sinus surgery can promote the recovery of symptoms and surgical cavity, and it is safe.