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目的了解住院尿路感染患者病原菌分布状况及耐药性特点。方法通过对尿液标本进行细菌分离培养、菌种鉴定及药敏试验,分析试验结果。结果调查期间分离出病原菌418株,其中革兰阴性菌占46.17%,革兰阳性菌占20.81%,真菌占33.01%。检出居前3位的病原菌为大肠埃希菌、热带假丝酵母菌和粪肠球菌;引起尿路感染的病原菌检出率,检出居前3位的科室为神经外科、泌尿外科和神经内科。检出病原菌对多数抗菌药物耐药。结论尿培养分离的病原菌以革兰阴性菌为主,真菌所占比例较高。临床应依据药敏试验结果合理选用抗菌药物。
Objective To understand the distribution and drug resistance of pathogenic bacteria in hospitalized urinary tract infection. Methods Urine samples were isolated and cultured bacteria, strain identification and drug sensitivity test, analysis of test results. Results 418 strains of pathogens were isolated during the investigation, of which, Gram-negative bacteria accounted for 46.17%, Gram-positive bacteria accounted for 20.81% and fungi accounted for 33.01%. The top 3 pathogenic bacteria were Escherichia coli, Candida tropicalis and Enterococcus faecalis. The detection rate of pathogenic bacteria causing urinary tract infection was highest in neurosurgery, urology and nerves Internal medicine. Pathogens detected most antibacterial drug resistance. Conclusions Gram-negative bacteria are the main pathogens isolated from urine culture, with a higher proportion of fungi. Clinical should be based on drug susceptibility test results reasonable selection of antimicrobial agents.