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目的:探讨同种异体移植型Kaposi肉瘤的发病率及其诊治。方法:回顾性分析我院773例肾移植受者中4例Kaposi肉瘤的发生情况和诊治经过。结果:肾移植术后Kaposi肉瘤发生率为0.52%,占同期发生的各类肿瘤的36.4%,发生时间分别为移植术后3、7、14和21个月,首发症状为咽喉痛、咽部异物感伴吞咽困难者2例,双下肢对称性多发紫红色斑丘疹并下肢水肿者2例,均经病理检查而确诊;治愈2例。结论:应提高对肾移植受者并发Kaposi肉瘤的认识,术后预防病毒感染,尽早行组织学检查,确诊后应立即减少或停用免疫抑制剂,必要时给予化疗或免疫增强剂
Objective: To investigate the incidence and diagnosis of allograft Kaposi’s sarcoma. Methods: Retrospective analysis of the incidence and diagnosis and treatment of Kaposi’s sarcoma in 773 renal transplant recipients in our hospital. Results: The incidence of Kaposi’s sarcoma after renal transplantation was 0.52%, which accounted for 36.4% of all types of tumors occurred in the same period. The time of occurrence was 3, 7, 14 and 21 months after transplantation. The first symptoms were sore throat and pharynx. Foreign body sensation with dysphagia was found in 2 patients. Symptomatic purpuric papules on both lower extremities and 2 cases of edema of the lower extremities were diagnosed by pathological examination. Two cases were cured. Conclusion: The knowledge of Kaposi’s sarcoma should be improved in renal transplant recipients. After the prevention of viral infection, histological examination should be performed as soon as possible. Immediately after diagnosis, immunosuppressants should be reduced or stopped. If necessary, chemotherapy or immunostimulants should be given.