目的 :探讨DIXON积分法在胆汁返流性胃炎病理诊断中的意义。方法 :选取我院 1 998年 5月～ 2 0 0 0年5月间行胃黏膜活检部分病例共 2 95例 ,从中选取BillrothⅡ病例 77例 ,作为残胃组 ;68例为胆汁返流组 ;1 0 0例为非胆汁返流组。常规HE染色按DIXON法进行病理形态学积分 ,同时记录幽门螺杆菌 (Helicobaetor Pylori,HP)的感染情况。结果 :毕 -Ⅱ占 37.7% ,显性返流符合 2 3 .2 % ,非返流组仅为 6 %。毕 -Ⅱ及显性返流组与非返流组的DIXON积分值有显著差异 ,HP亦少于非返流组 ,两组相比亦有显著差异。结论 :DIXON胆汁返流积分法可作为胆汁返流性胃炎的诊断指标。HP是否可作为一种胆汁返流性胃炎的诊断的指标 ,有待于进一步研究。 Objective: To explore the significance of DIXON integral in pathological diagnosis of bile reflux gastritis. Methods: A total of 2 95 cases of gastric mucosal biopsy were selected from May 1998 to May 2000 in our hospital. 77 patients with Billroth Ⅱ disease were selected as the gastric remnant group, 68 as the bile reflux group, One hundred and twenty non-biliary reflux groups. Conventional HE staining was performed according to DIXON method for histopathological integration, and Helicobacter pylori (HP) infection was recorded. Results: Bi-Ⅱ accounted for 37.7%, dominant reflux was 23.2%, non-reflux group was only 6%. There was a significant difference in DIXON integral between Bi-Ⅱand dominant reflux group and non-reflux group, and HP also had less difference than non-reflux group. There were also significant differences between the two groups. Conclusion: DIXON bile reflux integral method can be used as a diagnostic indicator of bile reflux gastritis. Whether HP can be used as an indicator of bile reflux gastritis needs further study.