我所于1975年从云南省路南县土壤中分离到一株紫色放线菌No.1289,经鉴定定名为紫色放线菌路南变种(Str.uiolaceusvar.lunanensis var.n.)。从该菌株的发酵液中分离到两个抗肿瘤蒽环类抗生素1289B_1(Rhodilunancin A)和1289B_2(Rho-dilunancin B)。从复合物酸水解产物中分到两种蒽环酮即配基Ⅰ和配基Ⅱ,经结构分析证明它们分别与γ-紫红霉酮(γ-rhodo-mycinone)、β-紫红霉酮(β-rhodomycino-ne)同质(图1)。 In 1975, I isolated a purple actinomycete No.1289 from the soil in Luonan County, Yunnan Province and identified it as Str.uiolaceusvar.lunanensis var.n. Two anti-tumor anthracyclines 1289B_1 (Rhodilunancin A) and 1289B_2 (Rho-dilunancin B) were isolated from the fermentation broth of this strain. Two kinds of anthracyclines, namely ligand I and ligand II, were separated from acid hydrolysates of the complex. Their structural analysis proved that they were related to γ-rhodo-mycinone, -rhodomycino-ne) (Figure 1).