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目的观察盐酸米诺环素软膏局部用药治疗慢性牙周炎的临床疗效。方法将76例慢性牙周炎患者按治疗药物不同分为对照组和治疗组各38例,对照组给予复方碘甘油治疗,治疗组给予盐酸米诺环素治疗,观察两组治疗后疗效和牙周袋指标变化。结果治疗组治疗4周后疗效显著优于对照组;两组治疗后牙龈指数和牙周袋深度均较治疗前明显改善,且治疗组改善程度显著优于对照组(P<0.05)。结论盐酸米诺环素软膏局部用药治疗慢性牙周炎疗效显著,可有效改善慢性牙周炎症状,值得推广应用。
Objective To observe the clinical effect of minocycline hydrochloride ointment for local treatment of chronic periodontitis. Methods Seventy-six patients with chronic periodontitis were divided into control group and treatment group according to the different therapeutic drugs. The control group was treated with compound iodoglycerin, the treatment group was treated with minocycline hydrochloride. The therapeutic effects and teeth Weekly bag index changes. Results After 4 weeks of treatment, the curative effect of the treatment group was significantly better than that of the control group. The gingival index and periodontal pocket depth of the two groups were significantly improved after treatment, and the treatment group improved significantly more than the control group (P <0.05). Conclusion Minocycline hydrochloride ointment for local treatment of chronic periodontitis has obvious curative effect, which can effectively improve the symptoms of chronic periodontitis and is worth popularizing and applying.