血管病变是糖尿病的重要并发症，其发生机理可能与血管内皮损伤有直接关系。血小板a颗粒膜糖蛋白（GMP－140）亦存在于内皮细胞的Weibel－Palade小体膜上，当血小板或内皮细胞活化破坏时，GMP－140可反映血小板或内皮细胞的活化程度和破坏情况。本文应用放射免疫法测定了糖尿病 Vascular disease is an important complication of diabetes, its mechanism may be directly related to vascular endothelial injury. GMP-140 is also present on the Weibel-Palade membrane of endothelial cells. When platelets or endothelial cells are activated and destroyed, GMP-140 can reflect the activation and destruction of platelets or endothelial cells. In this paper, the application of radioimmunoassay for the determination of diabetes