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目的通过病例报告正确认识造影剂脑病诊断和治疗。方法回顾性分析2例进行脑血管造影的患者,其中一例患者在造影后出现了逆行性遗忘,一例患者在介入治疗后出现了癫痫、昏迷。2例患者介入相关并发症均不是由于术中斑块脱落、脑出血、术后脑血流过度灌注以及支架内血栓形成等原因引起。结合相关文献复习,明确诊断为造影剂脑病。结果造影剂脑病临床表现多样,一旦确诊,应尽快积极处理,可防止脑功能不可逆损害的发生。结论造影剂脑病是一种临床罕见的由于造影剂不良反应引起的神经系统功能异常,早期预防以及正确处理非常关键。
Objective To correctly understand the diagnosis and treatment of contrast agent encephalopathy through case reports. Methods Two patients with cerebral angiography were retrospectively analyzed. One patient underwent retrograde amnesia after angiography. One patient developed epilepsy and coma after interventional therapy. Two cases of complications related to intervention were not caused by intraoperative plaque loss, cerebral hemorrhage, postoperative cerebral blood flow over-perfusion and stent thrombosis and other causes. Combined with relevant literature review, a clear diagnosis of contrast agent encephalopathy. Results The clinical manifestations of contrast agent encephalopathy, once diagnosed, should be actively dealt with as soon as possible to prevent the occurrence of irreversible brain damage. Conclusions Contrast-induced encephalopathy is a clinically rare neurological abnormality caused by adverse effects of contrast media. Early prevention and proper treatment are the keys.