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98例慢性血吸虫病患者随机分成治疗组、对照组。治疗组50例,吡喹酮60mg/kg,2d内4次分服,服吡喹酮前1周,口服甘草酸二胺胶囊150mg,日3次,共15d;对照组吡喹酮60mg/kg,2d内4次分服。治疗后1周检测丙氨酸氨基转移酶(ALT),治疗组为(40.62±2.65)U/L,对照组为(78.42±8.26)U/L,两组差异有统计学意义(P(0.05)。甘草酸二胺对预防吡喹酮肝功能损害有一定效果。
98 patients with chronic schistosomiasis were randomly divided into treatment group and control group. 50 cases of treatment group, praziquantel 60mg / kg, 2d within 4 times, 1 week before taking praziquantel, oral administration of glycyrrhizic acid diamine capsules 150mg, 3 times a day, a total of 15d; control group praziquantel 60mg / kg , 2d within 4 times service. The level of ALT in the treatment group was (40.62 ± 2.65) U / L and the control group was (78.42 ± 8.26) U / L, the difference was statistically significant (P (0.05) Glycyrrhizic acid diamine to prevent praziquantel liver function damage have a certain effect.