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目的:研究维吾尔族孕妇亚临床甲状腺功能减退症(SCH)的影响因素,提出防治对策。方法:选取2015年1月至2015年12月就诊于乌鲁木齐市妇幼保健院的且符合纳入及排除标准的维吾尔族孕妇,采用自行设计的调查问卷对选取的产妇进行面对面调查,收集并分析维吾尔族SCH患者的相关指标,将所有资料建立数据库,采用逐步向前法拟合多因素logistic回归模型探索SCH相关因素。结果:3428例维吾尔族中,妊娠期SCH患者490例,检出率为14.29%。通过逐步回归筛选表明,维吾尔族孕妇年龄、体质指数(BMI)、血红蛋白浓度、既往糖尿病病史对SCH的发生有影响(P<0.05)。年龄大于30岁、BMI大于24kg/m~2、贫血及既往合并糖尿病病史的维吾尔族孕妇发生SCH的风险较高。结论:高龄、肥胖、贫血、糖尿病是影响维吾尔族孕妇发生妊娠期SCH的主要因素。应加强孕前、孕期的健康宣教,避免高龄怀孕,控制孕期体质量,积极开展常见疾病监测及诊治,降低妊娠期SCH发生率。
Objective: To study the influencing factors of subclinical hypothyroidism (SCH) in pregnant women in Uighur and to propose prevention and cure measures. Methods: Uygur pregnant women who met the inclusion and exclusion criteria of Urumqi MCH from January 2015 to December 2015 were selected to conduct a face-to-face investigation on the selected mothers using a questionnaire designed by themselves to collect and analyze Uyghur SCH patients related indicators, all data will be built on the database, using step by step forward forward fitting multivariate logistic regression model to explore SCH related factors. Results: Of 3428 Uyghur nationality, 490 cases were diagnosed during pregnancy, the detection rate was 14.29%. The screening by stepwise regression showed that the age, body mass index (BMI), hemoglobin concentration and the history of previous diabetes in Uighur pregnant women had an impact on the occurrence of SCH (P <0.05). A pregnant woman of Uygur age older than 30 years and a BMI greater than 24 kg / m 2 has a higher risk of developing SCH with anemia and a history of previous DM. Conclusion: Older age, obesity, anemia and diabetes mellitus are the main factors affecting pregnant women with Uygur during pregnancy. Health education should be strengthened before and during pregnancy, to avoid pregnancy in old age, control the quality of pregnancy, and actively carry out monitoring and treatment of common diseases, reduce the incidence of SCH during pregnancy.