瑞氏(Rey)综合征在美国每年有几百人患病,发病率为2.7～2.8/10万(俄亥俄州)或2.4/10万(密执安州)。日本1981年10月—1982年3月6个月内发现54人临床上患本病者,可能尚不只此数。本病的病死率很高(日本40～50％,美国15—20％),早期发现及对脑水肿早期治疗很重要。本综合征与病毒感染所致中枢神经并发症有关,常发生于流行性感冒与水痘等病毒感染的恢复 Rey’s syndrome affects hundreds of people every year in the United States, with a prevalence of 2.7-2.8 / 100,000 (Ohio) or 2.4 / 100,000 (Michigan). Japan, October 1981 - March 1982 6 months found that 54 patients with this disease may not be the only number. The disease is highly fatal (40-50% in Japan and 15-20% in the United States), and early detection and early treatment of cerebral edema are important. The syndrome and central nervous system caused by viral infection related complications, often occurs in influenza and varicella and other viral infections recovery