肝血流阻断是肝切除术中控制出血的主要方法。目前临床手术中肝门阻断的方式有持续和间断两种，对两者所致肝线粒体和肝细胞结构功能变化的比较报道甚少。本实验采用大鼠肝缺血再灌注模型，比较两种方式对肝细胞损伤程度的差别。１　材料和方法１．１　动物及分组　ＳＤ雄性大 Hepatic blood flow occlusion is the primary method of controlling bleeding during hepatectomy. At present, there are two ways to block hepatic hilar in clinical operation, and there are few reports on the comparison of functional changes of hepatic mitochondria and hepatocytes caused by the two. In this study, rat liver ischemia-reperfusion model was used to compare the two methods of liver cell injury. 1 Materials and Methods 1.1 Animals and groups SD male large