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目的方法分析急性智齿冠周炎的细菌学特点并观察派丽奥对其治疗效果,为临床治疗提供参考。方法以2013年1-12月医院收治的98例急性智齿冠周炎患者为研究对象,取患者口腔组织标本,采用细菌鉴定仪对病原菌的分布及类型特点进行检测分析;同时,予以患者派丽奥(盐酸米诺环素软膏)治疗,评价治疗前后患者细菌密度及数量的变化。结果本组98例急性智齿冠周炎患者共检测出148株病原菌,位于前三位的致病菌依次为消化链球菌、口腔链球菌、微球菌;148株病原菌中,革兰阳性菌高于革兰阴性菌,差异有统计学意义(P<0.05);厌氧菌高于专性需氧菌及兼性厌氧菌差异有统计学意义(P<0.05);经派丽奥治疗后,患者细菌密度、螺旋体比例及革兰阴性菌比例较治疗前均下降差异均有统计学意义(P<0.05),革兰阳性菌比例较治疗前上升(P<0.05)。结论急性智齿冠周炎的主要病原菌为消化链球菌、口腔链球菌、微球菌;主要病原菌类型以革兰阳性菌和厌氧菌为主;派丽奥对急性智齿冠周炎具有良好的抗炎效果。
Objective To analyze the bacteriological characteristics of acute wisdom tooth pericoronitis and to observe the effect of treatment on it and provide a reference for clinical treatment. Methods A total of 98 patients with acute wisdom teeth pericoronitis were enrolled in the hospital from January to December in 2013. The samples of oral tissues were taken from the patients and the distribution and types of the pathogens were detected by bacterial identification instrument. Meanwhile, Austrian (minocycline hydrochloride ointment) treatment, evaluation of patients before and after treatment of bacterial density and quantity changes. Results A total of 148 pathogenic bacteria were detected in 98 patients with acute wisdom tooth pericoronitis. The pathogenic bacteria in the top three were Peptostreptococcus, Streptococcus oralis and Micrococcus. Among the 148 pathogenic bacteria, Gram-positive bacteria were higher than Gram-negative bacteria, the difference was statistically significant (P <0.05); anaerobic bacteria higher than obligate aerobic bacteria and facultative anaerobic bacteria was statistically significant (P <0.05) The bacterial density, the proportion of spirochetes and the proportion of Gram-negative bacteria in patients were significantly lower than those before treatment (P <0.05). The proportion of Gram-positive bacteria was higher than that before treatment (P <0.05). Conclusions The main pathogens of acute pericoronitis are Peptostreptococcus, Streptococcus oralis and Micrococcus. The main pathogens are Gram-positive bacteria and anaerobic bacteria. Paillio has a good anti-inflammation against acute pericoronitis effect.