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抗孕激素类药物米非司酮已广泛应用于临床终止早孕,当同前列腺素合并应用时,使流产率增加到90%以上.此方法安全、有效、疼痛轻.能较快地将完整的绒毛组织排出.现将我院1993年8～12月药物流产63例总结分析如下.1 临床资料1.1 对象 年龄在35岁以下确诊为早孕(停经<49天)自愿用药物流产、无前列腺素禁忌者.年龄20～35岁、平均27.4岁.妇科检查子宫大小与闻经天数符合;B超提示宫内孕、胎囊大小与闭经天数一致;尿HCG阳性.1.2 用药方法 采用国产米非司酮与米索前列醇两种口服药.第一日晨空腹或进食后2小时,用凉开水送服米非司酮150mg;第三日(48h后)上午8时空腹来院,用凉开水送服米索前列醇600μg.住院观察.1.3 结果63例中完全流产60例.失败3例,完全流产率为95.23%.在有妊娠史、无足月分娩史的22例中.完全流产21例、失败1例.在有妊娠史及分娩史
Anti-progesterone drugs mifepristone has been widely used in clinical termination of early pregnancy, when combined with prostaglandin, the abortion rate increased to 90%. This method is safe, effective, painful. Can quickly complete Villi tissue discharge now in our hospital from August to December 1993, 63 cases of medical abortion are summarized as follows.1 Clinical data 1.1 Subjects aged 35 years of age diagnosed as early pregnancy (menopause <49 days) Voluntary medical abortion without prostaglandin taboo .The age of 20 to 35 years old, average 27.4 years of gynecological examination uterus size and smell by the number of days; B ultrasound tips intrauterine pregnancy, fetal capsule size and the number of amenorrhea days; urine HCG positive.1.2 medication using domestic mifepristone And misoprostol two oral medication.First day morning or 2 hours after eating, with cold water delivery mifepristone 150mg; the third day (48h later) at 8 am fasting to the hospital, served with cold water Misoprostol 600μg. In hospital observation .1.3 results in 63 cases of complete abortion in 60 cases .Failed in 3 cases, the complete abortion rate was 95.23% .In a pregnant history, no full-term delivery history in 22 cases. Complete abortion in 21 cases, 1 case of failure in the history of pregnancy and childbirth history