柳叶刀杂志最近断言“中国有机会不仅在研究数量而且在研究质量上领导世界”[1]。没有理由排除上述权威预测适用于肾脏病领域研究的可能性。然而,如何实现这一目标呢?方法学严格的随机对照试验致力于解决与新的干预措施安全性及疗效有关的科研问题。成功的临床试验所不可或缺 The Lancet recently asserted that “China has the opportunity to lead the world not only in terms of quantity but also in research quality.” There is no reason to rule out the possibility that the above authoritative predictions apply to research in the field of kidney disease. However, how can this be achieved? A rigorous methodological randomized controlled trial is devoted to addressing scientific questions related to the safety and efficacy of new interventions. Successful clinical trials are indispensable