目前 ,国内外亲子鉴定案例中多采用ＳＴＲ基因座分型方法。由于ＳＴＲ序列核心序列短 ,在遗传过程发生变异的机会较高 ,已引起法医分子生物学和遗传学工作者的重视[1] 。但在父子二代的一家中有 2个ＳＴＲ基因座同时突变较为罕见 ,现报道如下。1　案情与检验结果1例因移民要求 At present, paternity testing at home and abroad and more cases using STR loci typing method. Due to the short sequence core sequence of STR, genetic mutation in the genetic process has a higher chance of causing forensic molecular biology and genetics workers attention [1]. However, in the second generation of the father and son, there are two STR loci simultaneously mutation is relatively rare, are reported below. 1 case and test results 1 case due to immigration requirements