自从应用类固醇治疗以来,肾病综合征的病死率下降,缓解率上升,疗效显著,但在治疗上尚存在不少问题。随着电子显微镜和萤光标记球蛋白抗体示踪检查法(简称萤光免疫检查法)的应用,肾脏活体组织检查质量有很大的提高,对肾病综合征的诊断、病理、临床和预后等方面都有了新的认识。在免疫抑制药物中环磷酰胺被认为是一种治疗肾病综合征疗效 Since the application of steroid therapy, nephrotic syndrome mortality decreased, the remission rate increased, the effect is significant, but there are still many problems in the treatment. With the application of electron microscopy and fluorescent labeled globulin antibody tracer method (hereinafter referred to as fluorescence immunoassay), the quality of renal biopsy has greatly improved, and the diagnosis, pathology, clinical and prognosis of nephrotic syndrome Have a new understanding of aspects. Cyclophosphamide is considered as a treatment of nephrotic syndrome in immunosuppressive drugs