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Two new hydrazone compounds,N’-(5-hydroxy-2-nitrobenzylidene)-4-dimethyl-aminobenzohydrazide methanol solvate (1) and 2-fluoro-N’-(5-hydroxy-2-nitrobenzylidene)benzo-hydrazide (2),have been synthesized and characterized by elemental analysis,IR spectra,1H NMR,and single-crystal X-ray diffraction.Compound 1 crystallizes in the monoclinic space group P21/c with a=11.571(3),b=12.420(3),c=12.360(2) ?,β=97.495(2)°,V=1761.1(7) 3,Z=4,R=0.0735 and wR=0.1344.Compound 2 crystallizes in the triclinic space group P with a=7.551(3),b=8.254(3),c=11.365(2) ?,α=79.352(2),β=76.154(2),γ=71.624(2)°,V=648.2(4) 3,Z=2,R=0.0393 and wR=0.1008.The hydrazone molecules of the compounds display E configurations with respect to the C=N double bonds.In the crystal structure of 1,the hydrazone molecules are linked by methanol molecules through N-H…O,O-H…N and O-H…O hydrogen bonds,forming chains running along the c axis.In the crystal structure of 2,molecules are linked through N-H…O and O-H…O hydrogen bonds,forming ribbons running along the b axis.The preliminary antimicrobial activities were studied.
Two new hydrazone compounds, N ’- (5-hydroxy-2-nitrobenzylidene) -4-dimethyl-aminobenzohydrazide methanol solvate (1) and 2-fluoro-N’- ), have been synthesized and characterized by elemental analysis, IR spectra, 1H NMR, and single-crystal X-ray diffraction. Compound 1 crystallizes in the monoclinic space group P21 / c with a = 11.571 (3), b = 12.420 , c = 12.360 (2)?,? = 97.495 (2) °, V = 1761.1 (7) 3, Z = 4, R = 0.0735 and wR = 0.1344. Compound 2 crystallizes in the triclinic space group P with a = 7.551 (3), b = 8.254 (3), c = 11.365 (2) ?,? = 79.352 (2),? = 76.154 (2),? = 71.624 (2) Z = 2, R = 0.0393 and wR = 0.1008. The hydrazone molecules of the compounds display E configurations with respect to the C = N double bonds. In the crystal structure of 1, the hydrazone molecules are linked by methanol molecules through NH ... O OH ... N and OH ... O hydrogen bonds, forming chains running along the c axis. In the crystal structure of 2, molecules are linked through NH ... O and OH ... O hydroge n bonds, forming ribbons running along the b axis. The preliminary antimicrobial activities were studied.