论文部分内容阅读
目的：探讨ＴＧＦβ１对人胃癌侵袭性的作用。方法：应用酶联免疫吸附法测定２９例胃癌病人血清转化生长因子（ＴＧＦ）β１浓度。结果：浸润型组或伴有淋巴结转移组的血清ＴＧＦβ１浓度分别明显高于膨胀型组或无淋巴结转移组（Ｐ＜０．０５～０．０１），切除瘤体后上述各组的血清ＴＧＦβ１浓度均明显下降（Ｐ＜０．０５～０．０１）。结论：ＴＧＦβ１可能与人胃癌的浸润和转移密切相关。
Objective: To investigate the effect of TGFβ1 on invasiveness of human gastric cancer. Methods: Serum transforming growth factor (TGFβ1) levels in 29 patients with gastric cancer were measured by enzyme-linked immunosorbent assay. Results: The serum concentration of TGFβ1 in infiltrative group or group with lymph node metastasis was significantly higher than that in infiltrative group or non-lymph node metastasis group (P <0.05-0.01). The serum levels of TGFβ1 Were significantly decreased (P <0.05 ~ 0.01). Conclusion: TGFβ1 may be closely related to the invasion and metastasis of human gastric cancer.