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肾综合征出血热(HFRS)是由不同血清型出血热病毒引起的一组疾病,其临床特征为发热、出血、肾损.目前命名至少有35个以上,1982年 WHO 统一命名为 HFRS,我国仍习惯沿用流行性出血热(EHF)之称。现就国外有关 HFRS 的临床研究概况作一介绍。病理生理、发病机理至今 HFRS 的发病机理尚未完全清楚,而对于病理生理的研究,国外主要集中在以下方面.血管损伤机理部分学者认为引起全身性毛细血管和小血管壁广泛性损伤的始动环节是病毒直接侵犯血管内皮细胞,但对病毒的嗜血管性尚无更多的
Hemorrhagic fever with renal syndrome (HFRS) is a group of diseases caused by different serotypes of hemorrhagic fever with clinical manifestations of fever, hemorrhage, and renal impairment Presently at least 35 have been named as the World Health Organization (WHO) Still used to epidemic hemorrhagic fever (EHF) said. Now on the foreign HFRS clinical research profile to make an introduction. Pathophysiology, pathogenesis The pathogenesis of HFRS has not yet fully understood, and for the study of pathophysiology, mainly in foreign countries focus on the following aspects of the mechanism of vascular injury Some scholars believe that systemic capillary and small vessel wall caused by extensive injury first move The virus is a direct violation of vascular endothelial cells, but the virus has no more blood vessels