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目的:对比观察社区2型糖尿病患者使用二甲双胍和格列吡嗪治疗的临床疗效。方法:2010年2月到2015年2月我院收治社区2型糖尿病患者60例,所有患者均经过临床检查确诊,根据治疗方法随机分为对照组和观察组,各占30例,分别使用二甲双胍和格列吡嗪治疗,对比观察社区2型糖尿病患者使用二甲双胍和格列吡嗪治疗的临床疗效。结果:经过治疗,观察组在治疗前后空腹血糖、餐后2h血糖及糖化血红蛋白等观察指标显著优于对照组,组间差异具有统计学意义(P<0.05)。结论:格列吡嗪应用于治疗社区2型糖尿病取得的临床疗效优于二甲双胍,值得在临床上广泛应用和推广。
Objective: To compare the clinical efficacy of metformin and glipizide in community-type 2 diabetes mellitus. Methods: From February 2010 to February 2015, 60 patients with type 2 diabetes mellitus were admitted to our hospital. All patients were diagnosed clinically. According to the treatment, they were randomly divided into control group and observation group, with 30 patients in each group. Metformin And glipizide treatment, compared to observe the community type 2 diabetes patients treated with metformin and glipizide in the clinical efficacy. Results: After treatment, fasting blood glucose, postprandial 2h blood glucose and glycosylated hemoglobin were significantly better in the observation group than those in the control group before and after treatment. The difference between the two groups was statistically significant (P <0.05). Conclusion: Glipizide is superior to metformin in the treatment of community type 2 diabetes mellitus, which is worth widely used in clinical practice.