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目的 研究导管内癌(ductalcarcinomainsitu ,DCIS)及伴微浸润(DCISwithmicroinvasion ,DCIS MI)患者的病理与临床特征。方法 对1999年6月至2 0 0 3年6月收治的4 1例DCIS及Ⅰ、Ⅱ型DCIS MI患者的临床和病理学特点进行回顾性研究。结果 DCIS及Ⅰ、Ⅱ型DCIS MI的病理学特点不同;首发症状中,9 76 %的患者仅表现为乳腺摄影钙化灶(5 0 %为DCIS) ;乳腺摄影检查诊断符合率为80 % ,Ⅱ型DCIS MI乳腺摄影表现为肿块和腺体紊乱的比例为33 3% ,高于DCIS和Ⅰ型DCIS MI;5 7%的患者表现为乳头溢液,乳管内视镜诊断符合率为95 6 5 % ;局部复发2例,均为Ⅱ型DCIS MI患者。结论 DCIS与Ⅰ型、Ⅱ型DCIS MI病理和临床表现各有特点,因而预后也不同。
Objective To study the pathological and clinical features of ductal carcinoma (DCIS) and patients with DCIS with microinvasion (DCIS MI). Methods The clinical and pathological features of 41 patients with DCIS and type Ⅰ and Ⅱ DCIS MI admitted from June 1999 to June 2003 were retrospectively studied. Results The pathological features of DCIS and DCIS MI were different from each other. Among the first symptom, 976% of the patients showed only mammography calcification (50%). The diagnostic accuracy of mammography was 80% The DCIS MI mammography showed a mass ratio of 33% of masses to glandular masses, higher than DCIS and type Ⅰ DCIS MI. Nipple discharge was found in 57% of patients, and the coincidence rate of endoscopic diagnosis was 95 6 5 %; Local recurrence in 2 cases, both type Ⅱ DCIS MI patients. Conclusion DCIS and type Ⅰ, type Ⅱ DCIS MI pathological and clinical manifestations of each have their own characteristics, so the prognosis is also different.