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目的探讨1例临床药师参与妊娠甲状腺功能亢进综合征引起肝功能损伤的药学监护。方法跟踪1例妊娠甲状腺功能亢进和肝功能损伤的患者妊娠期间主要诊疗经过,结合患者病史、妊娠期间的相关检查,分析其甲状腺功能亢进及肝损的原因,进而对临床用药提出合理化建议。结果患者患有妊娠甲状腺功能亢进综合征,进而引起肝功能损伤,在未经药物干预下,患者甲状腺功能随着妊娠周期延长明显好转。随着甲状腺功能亢进症状的好转,通过2种治疗肝损伤药物的联合应用,患者肝功能也逐步恢复正常。结论临床药师参与妊娠甲状腺功能亢进综合征引起肝功能损伤患者的药物治疗,可以促进临床合理用药,提高妊娠期患者用药的安全性。
Objective To investigate the pharmacological care of one case of clinical pharmacist involved in liver dysfunction caused by hyperthyroidism syndrome in pregnancy. Methods One case of pregnancy with hyperthyroidism and hepatic impairment was followed up during pregnancy. According to the history of patients and pregnancy, the causes of hyperthyroidism and liver damage were analyzed, and the reasonable suggestions for clinical medication were given. Results Patients with pregnancy-induced hyperthyroidism syndrome, which in turn lead to liver damage, without drug intervention, patients with thyroid function with prolonged pregnancy significantly improved. With the improvement of the symptoms of hyperthyroidism, the liver function of the patients also gradually returned to normal through the combination of two kinds of drugs for treating liver injury. Conclusion Clinical pharmacists participate in drug therapy of patients with liver dysfunction caused by hyperthyroidism syndrome in pregnancy, which can promote clinical rational use of drugs and improve the safety of patients during pregnancy.