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目的:观察山莨菪碱联合丽珠肠乐治疗腹泻型肠易激综合征的疗效。方法:将144例腹泻型肠易激综合征患者随机分为A组和B组,A组72例,给予消旋山莨菪碱片每次5m(g1片),每日3次,口服;丽珠肠乐每次0.7g(2粒),早晚各1次,餐后口服;B组72例,给予丽珠肠乐每次0.7g(2粒),早晚各1次,餐后口服,两组疗程均4周。结果:A组显效22例(30.6%),有效35例(48.6%),无效15例(20.8%),总有效52例(79.2%),B组显效16例(22.2%),有效25例(34.7%),无效31例(43.0%),总有效41例(57.0%);A组显效率和总有效率明显高于B组(P<0.05)。结论:山莨菪碱联合丽珠肠乐治疗腹泻型肠易激综合征疗效确切,无明显不良反应。
Objective: To observe the curative effect of anisodamine combined with Lizhuchangle on diarrhea-predominant irritable bowel syndrome. Methods: One hundred and forty-four patients with diarrhea-predominant irritable bowel syndrome were randomly divided into two groups: group A (72 cases) and group A (n = 72) Abdominal music each time 0.7g (2), morning and evening 1 times, after meals, oral; B group 72 cases, given Cabernet Franc each 0.7g (2 tablets), morning and evening 1 times, after oral administration, two Group therapy were 4 weeks. Results: In group A, there were 22 cases (30.6%) effective in 35 cases (48.6%), 15 cases (20.8%) ineffective, 52 cases (79.2%) effective in group A, 16 cases (22.2% (34.7%), 31 cases (43.0%) were ineffective and 41 cases (57.0%) were effective. The markedly effective rate and total effective rate in group A were significantly higher than those in group B (P <0.05). Conclusion: Anisodamine combined with Lizhu intestinal music for the treatment of diarrhea-predominant irritable bowel syndrome has the exact effect, no obvious adverse reactions.