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作者分析1949年—1979年期间的1122例特发性血小板减少性紫癜(ITP),随访至少已十年。作者认为从临床和实验室结果看,至少有两种类型的ITP。一种是变态型(744例)。平均发病年龄轻(13.9岁),发病前一个月内有细菌感染的105例(13.6%),有病毒感染的318例(占41.4%),早期出血症状较严重,自发缓解者418例(64.8%)。脾切除后缓解者24例(3.6%),内科治疗缓解者179例(27.1%),未获缓解者28例(4.4%),死亡1例。抗血小板因子在起病时阳性率为80.6%,恢复后仅4%为阳性。在非起病时有59例(8.9%)有过敏疾患。另一种是自家免疫型(348例)。症状出现缓慢,平均发病年龄较大(34.6岁),自行恢复的仅26例
The authors analyzed 1122 idiopathic thrombocytopenic purpura (ITP) cases from 1949 to 1979 and followed up for at least 10 years. The authors consider that there are at least two types of ITPs that are clinically and lab-results. One is metamorphosis (744 cases). There were 105 cases (13.6%) with bacterial infection within a month before onset, 318 cases (41.4%) with virus infection, and severe early-onset bleeding. 418 cases (64.8%) had spontaneous remission %). There were 24 cases (3.6%) of remission after splenectomy, 179 cases (27.1%) of remission of internal medicine, 28 cases (4.4%) without remission and 1 case of death. The anti-platelet factor positive rate was 80.6% at onset, only 4% after recovery was positive. There were 59 (8.9%) allergic disorders at non-onset. The other is self-immunotype (348 cases). Symptoms appear slow, the average age of onset is older (34.6 years), self-recovery in only 26 cases