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用SIVmac-CEM×174细胞系统筛选出中药,按照中医的辩证论治,将6味有抑制作用的中药组成“中药2号”复方,全方体外对SIVmac和HIV-1有抑制作用,正交t值法L12(2~(11))药味组合分析实验证明,其中有3味药为君药,极性提取法证明有效成分为水溶性部位,小鼠急性毒性实验未检测到致死剂量,最大耐受量超过人用量的225倍以上。
The traditional Chinese medicine was screened with the SIVmac-CEM×174 cell system. According to the dialectical treatment of traditional Chinese medicine, 6 herbs with inhibitory effects were combined to form a “TCM 2” compound, and the whole prescription had inhibitory effects on SIVmac and HIV-1 in vitro. The t-value method L12 (2~(11)) has been proved to be a combination of drug combinations. Among them, there are 3 tasting medicines as the king drug. The polarity extraction method proves that the active ingredient is a water-soluble part, and the mouse acute toxicity test does not detect a lethal dose. The tolerance is more than 225 times the amount of people.