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目的探讨舒肝解郁胶囊治疗中风后抑郁的临床疗效。方法选取2013年6月—2015年6月北京市中西医结合医院收治的轻中度中风后抑郁患者80例,按随机数字表法分为观察组与对照组,各40例。观察组患者予以舒肝解郁胶囊治疗,对照组患者予以盐酸帕罗西汀片治疗。观察两组患者临床疗效及不良反应发生情况。结果观察组患者总有效率高于对照组,差异有统计学意义(P<0.05);观察组患者口干、出汗、便秘和震颤发生率低于对照组,差异有统计学意义(P<0.05)。结论舒肝解郁胶囊治疗中风后抑郁的临床疗效显著,且不良反应少。
Objective To investigate the clinical efficacy of Shugan Jieyu Capsule in the treatment of post-stroke depression. Methods Eighty patients with mild to moderate stroke who were admitted to Beijing Hospital of Integrated Traditional Chinese and Western Medicine from June 2013 to June 2015 were selected and randomly divided into observation group and control group according to random number table. Patients in the observation group were treated with Shugan Jieyu capsules, and patients in the control group were treated with paroxetine hydrochloride tablets. The clinical efficacy and adverse reactions of the two groups were observed. Results The total effective rate of the observation group was higher than that of the control group (P <0.05). The incidences of dry mouth, sweating, constipation and tremor in the observation group were lower than those in the control group (P < 0.05). Conclusions Shugan Jieyu Capsule has significant clinical effect in treating post-stroke depression with few adverse reactions.