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对３０例健康人、３０例有自主神经病变症状的非胰岛素依赖型糖尿病（ＮＩＤＤＭ）患者、３０例无自主神经病变症状的ＮＩＤＤＭ患者进行心率变异（ＨＲＶ）的分析测定。结果：有自主神经病变症状的ＮＩＤＤＭ患者的时域测量（ＴＤ）及频域测量（ＦＤ）均显著低于正常人（Ｐ＜０．０１），无自主神经病变症状的ＮＩＤＤＭ患者ＴＤ及ＦＤ中的高原成分明显低于正常人（Ｐ＜０．０５）。说明糖尿病患者的心率变异性降低，有自主神经病变者交感、副交感神经损害均较重；无自主神经病变者也存在副交感神经损害。提示ＨＲＶ可作为早期诊断糖尿病自主神经病变的一个客观指标。
Heart rate variability (HRV) was measured in 30 healthy subjects, 30 non-insulin dependent diabetic (NIDDM) patients with autonomic neuropathy and 30 NIDDM patients without autonomic neuropathy. Results: The time domain (TD) and frequency domain (FD) of NIDDM patients with autonomic neuropathy were significantly lower than those of normal controls (P <0.01). The TD and FD of NIDDM patients without autonomic neuropathy The plateau composition was significantly lower than normal (P <0.05). Diabetes patients showed reduced heart rate variability, sympathetic autonomic neuropathy, parasympathetic damage were severe; no autonomic neuropathy also exist parasympathetic damage. Tip HRV can be used as an early diagnosis of diabetic autonomic neuropathy an objective indicator.