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近来年尿白蛋白（ＵＡＥ）作为糖尿病肾病（ＤＮ）重要诊断依据已被公认［１］，但有作者认为ＵＡＥ不能更早地提示糖尿病肾损伤［２］。ＤＮ早期病理改变是肾小球结节型和弥漫型硬化致肾缺血［３］，血尿内皮素（ＢＥＴ、ＵＥＴ）变化是肾缺血的敏感指标［４］。但是，关于糖
Urinary albumin (UAE) has been recognized as an important diagnostic basis for diabetic nephropathy (DN) in recent years [1]. However, some authors believe that UAE can not prompt diabetic nephropathy earlier. DN early pathological changes of glomerular nodules and diffuse sclerosis-induced renal ischemia [3], changes in urinary endothelin (BET, UET) is a sensitive indicator of renal ischemia [4]. But about sugar